7 nM in antagonism of monocyte chemoattractant protein-1 binding to hCCR2
Absorption of TAK-285 was rapid after oral dosing
ClH/c1-18(2)24(17-19-8-4-3-5-9-19)15-14-23(25)22-13-12-20-10-6-7-11-21(20)16-22
Ponatinib dosed orally for 19 days at 5
Methiothepin mesylate Size:2mg solid 7 nM in antagonism ofMethiothepin mesylate is a potent and non selective 5 HT2 receptor antagonist, with pKds of 7. 10 (5 HT1A), 7. 28 (5HT1B), 7. 56 (5HT1C), 6. 99 (5HT1D), 7. 0 (5 HT5A), 7. 8 (5 HT5B), 8. 74 (5 HT6), and 8. 99 (5 HT7), and pKis of 8. 50 (5HT2A), 8. 68 (5HT2B), and 8. 35 (5HT2C). Product information CAS Number: 74611 28 2 Molecular Weight: 452. 65 Formula: C21H28N2O3S3 Synonym: Metitepine mesylate Ro 8 6837 mesylate Chemical Name: 1 methyl 4 [6